Description

Chemical Composition IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1)

• CAS Number: 946870-92-4
• Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
• Molecular Weight: 9117.6 g/mol

Product Content

• IGF-1 LR3: 1mg
• Form: Lyophilized powder

Description IGF-1 LR3 is a synthetic, recombinant 83-amino acid peptide analogue of human Insulin-like Growth Factor-1 (IGF-1). It is supplied in a precisely measured 1mg formulation. This compound is intended strictly for laboratory research applications under controlled experimental environments. The peptide features an Arginine substitution at the third position and a 13-amino acid N-terminal extension. These structural modifications significantly reduce its affinity for Insulin-Like Growth Factor-Binding Proteins (IGFBPs), allowing for enhanced in vitro potency and an extended half-life compared to standard IGF-1. It is utilized primarily for cell culture applications, cellular signaling pathway analysis, and in vitro studies of cellular proliferation and survival. Each vial is manufactured under quality-controlled conditions to ensure consistency, high analytical purity, and experimental reproducibility.

Research Applications

• In vitro cellular proliferation and differentiation studies

• IGF-1 receptor (IGF-1R) binding and activation assays

• Cellular signaling pathway analysis (e.g., PI3K/AKT and MAPK pathways)

• Stem cell research and cell culture applications

• Experimental modeling of metabolic and muscle tissue regeneration

Storage and Handling

• Store at -20°C prior to reconstitution

• After reconstitution, store at 2–8°C

• Avoid repeated freeze-thaw cycles

• Protect from light and moisture

• Use sterile laboratory handling procedures

Product Specifications

• High analytical purity (≥99% HPLC Verified)

• Research-grade standard

• Appearance: White to off-white lyophilized powder

• Batch / Lot Number: ALX-012526-07

Compliance Notice FOR RESEARCH USE ONLY. Not for human or veterinary use. Not evaluated by the FDA. This product is intended strictly for laboratory and scientific research applications.