Description

Chemical Composition IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1)

• CAS Number: 946870-92-4
• Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉
• Molecular Weight: 9117.6 g/mol

Product Content

• IGF-1 LR3: 1mg
• Form: Lyophilized powder

Description IGF-1 LR3 is a synthetic, recombinant 83-amino acid peptide analogue of human Insulin-like Growth Factor-1 (IGF-1). It is supplied in a precisely measured 1mg formulation. This compound is intended strictly for laboratory research applications under controlled experimental environments. The peptide features an Arginine substitution at the third position and a 13-amino acid N-terminal extension. These structural modifications significantly reduce its affinity for Insulin-Like Growth Factor-Binding Proteins (IGFBPs), allowing for enhanced in vitro potency and an extended half-life compared to standard IGF-1. It is utilized primarily for cell culture applications, cellular signaling pathway analysis, and in vitro studies of cellular proliferation and survival. Each vial is manufactured under quality-controlled conditions to ensure consistency, high analytical purity, and experimental reproducibility.

Research Applications

• In vitro cellular proliferation and differentiation studies

• IGF-1 receptor (IGF-1R) binding and activation assays

• Cellular signaling pathway analysis (e.g., PI3K/AKT and MAPK pathways)

• Stem cell research and cell culture applications

• Experimental modeling of metabolic and muscle tissue regeneration

Storage and Handling

• Store at -20°C prior to reconstitution

• After reconstitution, store at 2–8°C

• Avoid repeated freeze-thaw cycles

• Protect from light and moisture

• Use sterile laboratory handling procedures

Product Specifications

• High analytical purity (≥99% HPLC Verified)

• Research-grade standard

• Appearance: White to off-white lyophilized powder

Compliance Notice FOR RESEARCH USE ONLY. Not for human or veterinary use. Not evaluated by the FDA. This product is intended strictly for laboratory and scientific research applications.